Staurosporine

CAS No.	62996-74-1	Cat. No.	BCP27724
Name	Staurosporine
Synonyms	AM-2282; AM2282; AM 2282; STS; Antibiotic 230; CGP 41251; CGP41251; CGP-41251; CCRIS 3272; Staurosporine;
Formula	C28H26N4O3	M. Wt	466.53

Description	Staurosporine, also known as antibiotic AM-2282 or STS, is a potent, non-selective inhibitor of protein kinases, including protein kinase C with promising anti-cancer activity. Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. Staurosporine was discovered to have biological activities ranging from anti-fungal to anti-hypertensive. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. Staurosporine is a prototypical ATP-competitive kinase inhibitor in that it binds to many kinases with high affinity.
Pathways	GPCR/G Protein Wnt/Stem Cell
Targets	PKA

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