Staurosporine
Data Sheet
For research use only. Not for human use.
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| CAS No. | 62996-74-1 | Cat. No. | BCP27724 |
| Name | Staurosporine | ||
| Synonyms | AM-2282; AM2282; AM 2282; STS; Antibiotic 230; CGP 41251; CGP41251; CGP-41251; CCRIS 3272; Staurosporine; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H26N4O3 | M. Wt | 466.53 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Staurosporine, also known as antibiotic AM-2282 or STS, is a potent, non-selective inhibitor of protein kinases, including protein kinase C with promising anti-cancer activity. Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. Staurosporine was discovered to have biological activities ranging from anti-fungal to anti-hypertensive. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. Staurosporine is a prototypical ATP-competitive kinase inhibitor in that it binds to many kinases with high affinity. | ||
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