LDN-212854

  • Chemical Properties
CAS No. 1432597-26-6 Cat. No. BCP08633
Name LDN-212854
Synonyms LDN212854;LDN 212854;
Formula C25H22N6 M. Wt 406.48
  • Biological Activity
Description LDN-212854 is a novel BMP inhibitor that exhibits substantially greater selectivity for BMP versus the TGF-β type I receptors; possesses a bias towards ALK2(IC50=1.3 nM) versus ALK1 and ALK3 compared to other inhibitors.
Pathways TGF beta/Smad  
Targets BMP/TGF beta Receptor 

Structure

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