Y15 tetrahydrochloride
| CAS No. | 4506-66-5 | Cat. No. | BCP27854 |
| Name | Y15 tetrahydrochloride | ||
| Synonyms | Y 15; Y15;Y-15;FAK inhibitor Y15; FAK Inhibitor 14; | ||
| Formula | C6H14Cl4N4 | M. Wt | 284.01 |
| Description | Y15 is a novel small molecule FAK phosphorylation inhibitor. It is a direct inhibitor of FAK1 autophosphorylation, blocking phosphorylation of Y397. Besides, it promotes cell detachment and inhibits cell adhesion of cells in culture. It has been used to demonstrate a role for FAK in the regulation of aortic stiffness. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FAK | ||
Structure
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