Y15 tetrahydrochloride New
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CAS No. | 4506-66-5 | Cat. No. | BCP27854 |
Name | Y15 tetrahydrochloride | ||
Synonyms | Y 15; Y15;Y-15;FAK inhibitor Y15; FAK Inhibitor 14; | ||
SMILES | C1=C(C(=CC(=C1N)N)N)N.Cl.Cl.Cl.Cl | ||
Chemical Name | |||
Formula | C6H14Cl4N4 | M. Wt | 284.01 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Y15 is a novel small molecule FAK phosphorylation inhibitor. It is a direct inhibitor of FAK1 autophosphorylation, blocking phosphorylation of Y397. Besides, it promotes cell detachment and inhibits cell adhesion of cells in culture. It has been used to demonstrate a role for FAK in the regulation of aortic stiffness. |
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