Avibactam sodium

  • Chemical Properties
CAS No. 1192491-61-4 Cat. No. BCP08818
Name Avibactam sodium
Synonyms NXL104;NXL-104;NXL 104;Avibactam Sodium Salt;
Formula C7H10N3NaO6S M. Wt 287.23
  • Biological Activity
Description Avibactam Sodium is a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens.
Related Products 1192500-31-4(Avibactam) DA(脱羰基阿维巴坦) Avibactam Impurity(Avibactam Impurity) AVH(Avibactam sodium hydrate)
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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