Avibactam sodium
CAS No. | 1192491-61-4 | Cat. No. | BCP08818 |
Name | Avibactam sodium | ||
Synonyms | NXL104;NXL-104;NXL 104;Avibactam Sodium Salt; | ||
Formula | C7H10N3NaO6S | M. Wt | 287.23 |
Description | Avibactam Sodium is a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. | ||
Related Products | 1192500-31-4(Avibactam) DA(脱羰基阿维巴坦) Avibactam Impurity(Avibactam Impurity) AVH(Avibactam sodium hydrate) | ||
Pathways | Microbiology/Virology | ||
Targets | Antibiotic |
Novel Specific Metallo-β-Lactamase Inhibitor ANT2681 Restores Meropenem Activity to Clinically Effective Levels against NDM-Positive Enterobacterales
Publications Citing of Biochempartner's Avibactam sodium(CAS:1192491-61-4) |
Structure
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