Avibactam sodium New
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CAS No. | 1192491-61-4 | Cat. No. | BCP08818 |
Related Products | 1192500-31-4(Avibactam) DA(脱羰基阿维巴坦) Avibactam Impurity(Avibactam Impurity) AVH(Avibactam sodium hydrate) | ||
Name | Avibactam sodium | ||
Synonyms | NXL104;NXL-104;NXL 104;Avibactam Sodium Salt; | ||
SMILES | C1CC(N2CC1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+] | ||
Chemical Name | |||
Formula | C7H10N3NaO6S | M. Wt | 287.23 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Avibactam Sodium is a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. |
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