CW069
CAS No. | 1594094-64-0 | Cat. No. | BCP27898 |
Name | CW069 | ||
Synonyms | CW069; CW 069; | ||
Formula | C23H21IN2O3 | M. Wt | 500.33 |
Description | CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | Kinesin |
Structure
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