CW069

  • Chemical Properties
CAS No. 1594094-64-0 Cat. No. BCP27898
Name CW069
Synonyms CW069; CW 069;
Formula C23H21IN2O3 M. Wt 500.33
  • Biological Activity
Description CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics.
Pathways Cell Cycle/DNA Damage 
Targets Kinesin 

Structure

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