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CAS No. | 1594094-64-0 | Cat. No. | BCP27898 |
Name | CW069 | ||
Synonyms | CW069; CW 069; | ||
SMILES | C1=CC=C(C=C1)CC(C(=O)NC2=C(C=C(C=C2)I)C(=O)O)NCC3=CC=CC=C3 | ||
Chemical Name | |||
Formula | C23H21IN2O3 | M. Wt | 500.33 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics. |
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