AK-7
| CAS号 | 420831-40-9 | 货号 | BCP09325 |
| 中文名 | AK-7 | ||
| 英文名 | AK-7 | ||
| 中文别名 | |||
| 英文别名 | AK 7;AK7; | ||
| 分子式 | C19H21BrN2O3S | 分子量 | 437.35 |
| 生物活性 | AK-7 treated R6/2 mice performed significantly better than vehicle treated littermates on the accelerating rotarod at 8 and 11 weeks of age. AK-7 at the 10mg/kg dose was also effective in extending the survival of R6/2 mice. Mean survival of placebo treated R6/2 mice was 94.8±5.4, as compared with 109.2± 2.6 in AK-7 treated (10mg/kg) mice; mean survival of treated R6/2 mice was increased by 13.2%. At the 20 mg/kg dose, treatment with AK-7 caused a non-significant trend towards survival extension. | ||
| 信号通路 | Cell Cycle/DNA Damage Epigenetics | ||
| 靶 点 | Sirtuin | ||
结构式
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