Bucladesine sodium

CAS No.	16980-89-5	Cat. No.	BCP09391
Name	Bucladesine sodium
Synonyms	Dibutyryl-cAMP, sodium salt; DBcAMP sodium salt;
Formula	C18H23N5NaO8P	M. Wt	491.37

Description	Bucladesine sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP.
Pathways	GPCR/G Protein Wnt/Stem Cell
Targets	PKA

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