Bucladesine sodium New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 16980-89-5 | Cat. No. | BCP09391 |
| Name | Bucladesine sodium | ||
| Synonyms | Dibutyryl-cAMP, sodium salt; DBcAMP sodium salt; | ||
| SMILES | CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+] | ||
| Chemical Name | |||
| Formula | C18H23N5NaO8P | M. Wt | 491.37 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Bucladesine sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP. | ||
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