Sivelestat sodium tetrahydrate

  • Chemical Properties
CAS No. 201677-61-4 Cat. No. BCP09535
Name Sivelestat sodium tetrahydrate
Synonyms EI546 sodium tetrahydrate; LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate;Ono-EI-600 sodium tetrahydrate;
Formula C20H29N2NaO11S M. Wt 528.51
  • Biological Activity
Description Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
Related Products 150374-95-1(Sivelestat sodium) 127373-66-4(Sivelestat)
Pathways Protease/Metabolic Enzyme 
Targets Elastase 

Structure

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