Sivelestat sodium New
Data Sheet
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| CAS No. | 150374-95-1 | Cat. No. | BCP09709 |
| Related Products | 127373-66-4（Sivelestat） 201677-61-4（Sivelestat sodium tetrahydrate） | ||
| Name | Sivelestat sodium | ||
| Synonyms | Sivelestat sodium salt;ONO5046-Na;Sodium sivelestat;EI546 sodium;LY544349 sodium; | ||
| SMILES | CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+] | ||
| Chemical Name | |||
| Formula | C20H21N2NaO7S | M. Wt | 456.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil transmigration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo. | ||
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