Sivelestat sodium
| CAS No. | 150374-95-1 | Cat. No. | BCP09709 |
| Name | Sivelestat sodium | ||
| Synonyms | Sivelestat sodium salt;ONO5046-Na;Sodium sivelestat;EI546 sodium;LY544349 sodium; | ||
| Formula | C20H21N2NaO7S | M. Wt | 456.44 |
| Description | Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil transmigration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo. | ||
| Related Products | 127373-66-4（Sivelestat） 201677-61-4（Sivelestat sodium tetrahydrate） | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Elastase | ||
Structure
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