1-金刚烷胺
| CAS号 | 768-94-5 | 货号 | BCP09869 |
| 中文名 | 1-金刚烷胺 | ||
| 英文名 | Amantadine | ||
| 中文别名 | |||
| 英文别名 | ADS-5102, EXP 105-1; EXP-105-1; GP 38026; | ||
| 分子式 | C10H17N | 分子量 | 151.25 |
| 生物活性 | Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Influenza Virus | ||
结构式
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