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Amantadine 结构式

1-金刚烷胺

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货号 :BCP09869CAS号 :768-94-5纯度:98%
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  • 基本信息与产品描述
CAS号 768-94-5 货号 BCP09869
中文名 1-金刚烷胺
英文名 Amantadine
中文别名
英文别名 ADS-5102, EXP 105-1; EXP-105-1; GP 38026;
SMILES
化学名称
分子式 C10H17N 分子量 151.25
纯度 98% 配送 惯例下常温包邮
产品描述 Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine.
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