Phloretin

  • Chemical Properties
CAS No. 60-82-2 Cat. No. BCP28296
Name Phloretin
Synonyms NSC 407292; NSC-407292; NSC407292; RJC 02792; RJC02792; RJC-02792;
Formula C15H14O5 M. Wt 274.27
  • Biological Activity
Description Phloretin, also known as NSC 407292 and RJC 02792. is a dihydrochalcone flavonoid, is mainly found in fruit, leaves, and roots of apple tree. Phloretin inhibits a variety of transporters. Phloretin inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively). Phloretin exerts antioxidant, anti-inflammatory, and anti-tumor activities in mammalian cells).
Pathways Ion Channel/Membrane Transporter GPCR/G Protein 
Targets SGLT 

Structure

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