Phloretin
CAS No. | 60-82-2 | Cat. No. | BCP28296 |
Name | Phloretin | ||
Synonyms | NSC 407292; NSC-407292; NSC407292; RJC 02792; RJC02792; RJC-02792; | ||
Formula | C15H14O5 | M. Wt | 274.27 |
Description | Phloretin, also known as NSC 407292 and RJC 02792. is a dihydrochalcone flavonoid, is mainly found in fruit, leaves, and roots of apple tree. Phloretin inhibits a variety of transporters. Phloretin inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively). Phloretin exerts antioxidant, anti-inflammatory, and anti-tumor activities in mammalian cells). | ||
Pathways | Ion Channel/Membrane Transporter GPCR/G Protein | ||
Targets | SGLT |
Structure
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