Ronacaleret HCl

CAS No.	702686-96-2	Cat. No.	BCP11469
Name	Ronacaleret HCl
Synonyms	Ronacaleret;SB751689; SB-751689; SB 751689; SB751689A; SB-751689A; SB 751689A; SB751689-A;
Formula	C25H32ClF2NO4	M. Wt	483.98

Description	Ronacaleret, also known as SB751689, is an orally-active calcium-sensing receptor (CaSR) antagonist that has the potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34) (rhPTH(1-34)). Administration of ronacaleret led to lower peak levels of PTH than were observed with rhPTH(1-34), however, greater total PTH exposure was observed.
Pathways	GPCR/G Protein
Targets	CaSR

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