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CAS No. | 702686-96-2 | Cat. No. | BCP11469 |
Name | Ronacaleret HCl | ||
Synonyms | Ronacaleret;SB751689; SB-751689; SB 751689; SB751689A; SB-751689A; SB 751689A; SB751689-A; | ||
SMILES | CC(C)(CC1CC2=CC=CC=C2C1)NCC(COC3=C(C(=CC(=C3)CCC(=O)O)F)F)O.Cl | ||
Chemical Name | |||
Formula | C25H32ClF2NO4 | M. Wt | 483.98 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Ronacaleret, also known as SB751689, is an orally-active calcium-sensing receptor (CaSR) antagonist that has the potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34) (rhPTH(1-34)). Administration of ronacaleret led to lower peak levels of PTH than were observed with rhPTH(1-34), however, greater total PTH exposure was observed. |
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