Safinamide

  • Chemical Properties
CAS No. 133865-89-1 Cat. No. BCP12082
Name Safinamide
Synonyms EMD 1195686;FCE 26743;EMD-1195686;EMD1195686;FCE-26743;
Formula C17H19FN2O2 M. Wt 302.34
  • Biological Activity
Description Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.
Pathways Neuro Signaling Pathway 
Targets Monoamine Oxidase 

Structure

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