Safinamide
Data Sheet
For research use only. Not for human use.
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| CAS No. | 133865-89-1 | Cat. No. | BCP12082 |
| Name | Safinamide | ||
| Synonyms | EMD 1195686;FCE 26743;EMD-1195686;EMD1195686;FCE-26743; | ||
| SMILES | C[C@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C(N)=O | ||
| Chemical Name | |||
| Formula | C17H19FN2O2 | M. Wt | 302.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals. | ||
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