(S)-Ketorolac

  • Chemical Properties
CAS No. 66635-92-5 Cat. No. BCP28452
Name (S)-Ketorolac
Synonyms Ketorolac S-Isomer;(-)-Ketorolac;
Formula C15H13NO3 M. Wt 255.26
  • Biological Activity
Description (S)-ketorolac is a 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It has a role as an analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor and a non-steroidal anti-inflammatory drug. It is an enantiomer of a (R)-ketorolac.
Pathways Neuro Signaling Pathway 
Targets COX 

Structure

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