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CAS No. | 66635-92-5 | Cat. No. | BCP28452 |
Name | (S)-Ketorolac | ||
Synonyms | Ketorolac S-Isomer;(-)-Ketorolac; | ||
SMILES | C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O | ||
Chemical Name | |||
Formula | C15H13NO3 | M. Wt | 255.26 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (S)-ketorolac is a 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It has a role as an analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor and a non-steroidal anti-inflammatory drug. It is an enantiomer of a (R)-ketorolac. |
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