Nolatrexed
| CAS No. | 147149-76-6 | Cat. No. | BCP12638 |
| Name | Nolatrexed | ||
| Synonyms | AG337; AG 337; AG-337; | ||
| Formula | C14H12N4OS | M. Wt | 284.34 |
| Description | Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Hence, it does not warrant further study as a single agent for this disease. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Thymidylate Synthase | ||
Structure
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