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CAS No. | 147149-76-6 | Cat. No. | BCP12638 |
Name | Nolatrexed | ||
Synonyms | AG337; AG 337; AG-337; | ||
SMILES | |||
Chemical Name | |||
Formula | C14H12N4OS | M. Wt | 284.34 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Hence, it does not warrant further study as a single agent for this disease. |
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