MDK-1699

  • Chemical Properties
CAS No. 432001-69-9 Cat. No. BCP28593
Name MDK-1699
Synonyms MDK 1699; MDK1699; Skp2 inhibitor C1;SKPin C1;
Formula C18H13BrN2O4S2 M. Wt 465.34
  • Biological Activity
Description MDK-1699, also known as Skp2 inhibitor C1 and SKPin C1, is a Skp2 inhibitor. MDK-1699 inhibits Skp2-mediated p27 degradation; induces cell cycle arrest.MDK-1699 is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibited Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.
Pathways Protease/Metabolic Enzyme 
Targets E1 E2 E3 Enzyme 

Structure

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