MDK-1699
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CAS No. | 432001-69-9 | Cat. No. | BCP28593 |
Name | MDK-1699 | ||
Synonyms | MDK 1699; MDK1699; Skp2 inhibitor C1;SKPin C1; | ||
SMILES | C1=CC(=CN=C1)CN2C(=O)C(=CC3=C(C=CC(=C3)Br)OCC(=O)O)SC2=S | ||
Chemical Name | |||
Formula | C18H13BrN2O4S2 | M. Wt | 465.34 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MDK-1699, also known as Skp2 inhibitor C1 and SKPin C1, is a Skp2 inhibitor. MDK-1699 inhibits Skp2-mediated p27 degradation; induces cell cycle arrest.MDK-1699 is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibited Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts. |
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