Mutated EGFR-IN-1
| CAS No. | 1421372-66-8 | Cat. No. | BCP28639 |
| Name | Mutated EGFR-IN-1 | ||
| Synonyms | AZD9291-Des acryl analogue;Osimertinib analog;AZD9291DA; | ||
| Formula | C25H31N7O | M. Wt | 445.57 |
| Description | Mutated EGFR-IN-1 is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | EGFR | ||
Structure
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