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Mutated EGFR-IN-1 Chemical Structure

Mutated EGFR-IN-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28639CAS No. :1421372-66-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1421372-66-8 Cat. No. BCP28639
Name Mutated EGFR-IN-1
Synonyms AZD9291-Des acryl analogue;Osimertinib analog;AZD9291DA;
SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC
Chemical Name
Formula C25H31N7O M. Wt 445.57
Purity 98% Storage Store at 4-8°C
Description Mutated EGFR-IN-1 is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models.
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