Mutated EGFR-IN-1
| CAS号 | 1421372-66-8 | 货号 | BCP28639 |
| 中文名 | Mutated EGFR-IN-1 | ||
| 英文名 | Mutated EGFR-IN-1 | ||
| 中文别名 | AZD9291中间体1;奥希替尼中间体1; | ||
| 英文别名 | AZD9291-Des acryl analogue;Osimertinib analog;AZD9291DA; | ||
| 分子式 | C25H31N7O | 分子量 | 445.57 |
| 生物活性 | Mutated EGFR-IN-1 is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | EGFR | ||
结构式
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