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CAS号 | 1421372-66-8 | 货号 | BCP28639 |
中文名 | Mutated EGFR-IN-1 | ||
英文名 | Mutated EGFR-IN-1 | ||
中文别名 | AZD9291中间体1;奥希替尼中间体1; | ||
英文别名 | AZD9291-Des acryl analogue;Osimertinib analog;AZD9291DA; | ||
SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC | ||
化学名称 | |||
分子式 | C25H31N7O | 分子量 | 445.57 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Mutated EGFR-IN-1 is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. |
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