Dipraglurant
| CAS No. | 872363-17-2 | Cat. No. | BCP23706 |
| Name | Dipraglurant | ||
| Synonyms | ADX-48621; ADX48621; ADX 48621; | ||
| Formula | C16H12FN3 | M. Wt | 265.29 |
| Description | Dipraglurant is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID). Blocking metabotropic glutamate receptor type 5 (mGluR5) has been proposed as a target for levodopa-induced dyskinesias (LID) in Parkinson's disease (PD). Acute challenges of dipraglurant were efficacious on choreic and dystonic LID in the MPTP-macaque model. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mGluR | ||
Structure
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