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Dipraglurant Chemical Structure

Dipraglurant

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23706CAS No. :872363-17-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 872363-17-2 Cat. No. BCP23706
Name Dipraglurant
Synonyms ADX-48621; ADX48621; ADX 48621;
SMILES C1=CC=NC(=C1)C#CCCC2=CN3C=C(C=CC3=N2)F
Chemical Name
Formula C16H12FN3 M. Wt 265.29
Purity 98% Storage Store at 4-8°C
Description Dipraglurant is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID). Blocking metabotropic glutamate receptor type 5 (mGluR5) has been proposed as a target for levodopa-induced dyskinesias (LID) in Parkinson's disease (PD). Acute challenges of dipraglurant were efficacious on choreic and dystonic LID in the MPTP-macaque model.
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