MDL-28170
| CAS No. | 88191-84-8 | Cat. No. | BCP15636 |
| Name | MDL-28170 | ||
| Synonyms | Calpain Inhibitor III;MDL 28170;MDL28170; | ||
| Formula | C17H17NO3 | M. Wt | 283.32 |
| Description | MDL 28170 is a selective inhibitor, which inhibites calpain with Ki values of 10nM and cathepsin B with Ki values of 25 nM while does not inhibit trypsin-like serine proteases. And it can penetrate the blood–brain barrier rapidly and show the activity in inhibiting brain cysteine protease activity following systemic administration. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Cathepsin | ||
Structure
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