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CAS No. | 88191-84-8 | Cat. No. | BCP15636 |
Name | MDL-28170 | ||
Synonyms | Calpain Inhibitor III;MDL 28170;MDL28170; | ||
SMILES | |||
Chemical Name | |||
Formula | C17H17NO3 | M. Wt | 283.32 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MDL 28170 is a selective inhibitor, which inhibites calpain with Ki values of 10nM and cathepsin B with Ki values of 25 nM while does not inhibit trypsin-like serine proteases. And it can penetrate the blood–brain barrier rapidly and show the activity in inhibiting brain cysteine protease activity following systemic administration. |
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