Verubecestat

  • Chemical Properties
CAS No. 1286770-55-5 Cat. No. BCP15722
Name Verubecestat
Synonyms MK 8931;MK-8931;SCH 900931;SCH900931;SCH-900931;MK8931;
Formula C17H17F2N5O3S M. Wt 409.41
  • Biological Activity
Description MK-8931, also known as Verubecestat or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.
Pathways Neuro Signaling Pathway 
Targets Beta secretase 

Structure

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