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CAS No. | 1286770-55-5 | Cat. No. | BCP15722 |
Name | Verubecestat | ||
Synonyms | MK 8931;MK-8931;SCH 900931;SCH900931;SCH-900931;MK8931; | ||
SMILES | O=C(C1=NC=C(F)C=C1)NC2=CC=C(F)C([C@@](C3)(C)N=C(N)N(C)S3(=O)=O)=C2 | ||
Chemical Name | |||
Formula | C17H17F2N5O3S | M. Wt | 409.41 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MK-8931, also known as Verubecestat or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. |
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