BD-1047二氢溴酸盐
| CAS号 | 138356-21-5 | 货号 | BCP15756 |
| 中文名 | BD-1047二氢溴酸盐 | ||
| 英文名 | BD1047 dihydrobromide | ||
| 中文别名 | |||
| 英文别名 | BD-1047 dihydrobromide;BD 1047 dihydrobromide; BD-1047 2HBr; | ||
| 分子式 | C13H20Cl2N2.2HBr | 分子量 | 437.04 |
| 生物活性 | BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.BD1047 is a potent and selective Sigma-1 Receptor Antagonist. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Sigma Receptor | ||
结构式
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