Liproxstatin-1
| CAS No. | 950455-15-9 | Cat. No. | BCP15985 |
| Name | Liproxstatin-1 | ||
| Synonyms | Liproxstatin 1;Liproxstatin1; | ||
| Formula | C19H21ClN4 | M. Wt | 340.85 |
| Description | Liproxstatin-1 is a potent ferroptosis inhibitor in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage. Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). Ferroptosis is a non-apoptotic form of cell death induced by small molecules in specific tumour types, and in engineered cells overexpressing oncogenic RAS. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Ferroptosis | ||
Structure
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