Liproxstatin-1
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CAS No. | 950455-15-9 | Cat. No. | BCP15985 |
Name | Liproxstatin-1 | ||
Synonyms | Liproxstatin 1;Liproxstatin1; | ||
SMILES | |||
Chemical Name | |||
Formula | C19H21ClN4 | M. Wt | 340.85 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Liproxstatin-1 is a potent ferroptosis inhibitor in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage. Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). Ferroptosis is a non-apoptotic form of cell death induced by small molecules in specific tumour types, and in engineered cells overexpressing oncogenic RAS. |
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