Lenrispodun

  • Chemical Properties
CAS No. 1160521-50-5 Cat. No. BCP16186
Name Lenrispodun
Synonyms ITI-214; ITI 214; ITI214; PDE1-IN-1;PDE4 (R)-(-)-Rolipram;
Formula C29H26FN7O M. Wt 507.56
  • Biological Activity
Description ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders.
Related Products 1642303-38-5(Lenrispodun phosphate)
Pathways Protease/Metabolic Enzyme 
Targets Phosphodiesterase/PDE 

Structure

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