Lenrispodun phosphate New
Data Sheet
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| CAS No. | 1642303-38-5 | Cat. No. | BCP44187 |
| Related Products | 1160521-50-5（Lenrispodun） | ||
| Name | Lenrispodun phosphate | ||
| Synonyms | ITI-214; ITI 214; ITI214; ITI-214 phosphate salt;PDE1-IN-1 phosphate;ITI-214 phosphate; | ||
| SMILES | CN1C(=O)C2=C(N(N=C2N3C1=NC4C3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7.OP(=O)(O)O | ||
| Chemical Name | |||
| Formula | C29H29FN7O5P | M. Wt | 605.57 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders. | ||
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