ISRIB (trans-isomer)
| CAS No. | 1597403-47-8 | Cat. No. | BCP23947 |
| Name | ISRIB (trans-isomer) | ||
| Synonyms | trans-ISRIB; | ||
| Formula | C22H24Cl2N2O4 | M. Wt | 451.34 |
| Description | ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PERK | ||
Structure
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