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ISRIB (trans-isomer) Chemical Structure

ISRIB (trans-isomer)

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23947CAS No. :1597403-47-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1597403-47-8 Cat. No. BCP23947
Name ISRIB (trans-isomer)
Synonyms trans-ISRIB;
SMILES C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
Chemical Name
Formula C22H24Cl2N2O4 M. Wt 451.34
Purity 98% Storage Store at 4-8°C
Description ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.
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