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CAS No. | 1597403-47-8 | Cat. No. | BCP23947 |
Name | ISRIB (trans-isomer) | ||
Synonyms | trans-ISRIB; | ||
SMILES | C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl | ||
Chemical Name | |||
Formula | C22H24Cl2N2O4 | M. Wt | 451.34 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells. |
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