NQDI-1
| CAS No. | 175026-96-7 | Cat. No. | BCP16684 |
| Name | NQDI-1 | ||
| Synonyms | NQDI 1;NQDI1; | ||
| Formula | C19H13NO4 | M. Wt | 319.31 |
| Description | NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. NQDI-1 was used to study LPS-induced activation and role of ASK1 and p38 in anti-inflammatory cytokine production by macrophages Apoptosis signal-regulating kinase 1 (ASK1) is among the signaling events that lead to postischemic cell death. Inhibition of ASK1 pathway protected hearts from ischemic damage. | ||
| Pathways | MAPK Pathway | ||
| Targets | MAP3K | ||
Structure
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