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NQDI-1 Chemical Structure

NQDI-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP16684CAS No. :175026-96-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 175026-96-7 Cat. No. BCP16684
Name NQDI-1
Synonyms NQDI 1;NQDI1;
SMILES CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O
Chemical Name
Formula C19H13NO4 M. Wt 319.31
Purity 98% Storage Store at 4-8°C
Description NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. NQDI-1 was used to study LPS-induced activation and role of ASK1 and p38 in anti-inflammatory cytokine production by macrophages Apoptosis signal-regulating kinase 1 (ASK1) is among the signaling events that lead to postischemic cell death. Inhibition of ASK1 pathway protected hearts from ischemic damage.
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