Nastorazepide
| CAS No. | 209219-38-5 | Cat. No. | BCP16894 |
| Name | Nastorazepide | ||
| Synonyms | Z-360;Z 360;Z360; | ||
| Formula | C29H36N4O5 | M. Wt | 520.62 |
| Description | in vitro: Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells. Check for active clinical trials or closed clinical trials using this agent. in vivo: Z-360 is a novel orally active CCK-2/gastrin receptor antagonist, significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Z-360 combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Cholecystokinin Receptor | ||
Structure
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