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Nastorazepide Chemical Structure

Nastorazepide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP16894CAS No. :209219-38-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 209219-38-5 Cat. No. BCP16894
Name Nastorazepide
Synonyms Z-360;Z 360;Z360;
SMILES
Chemical Name
Formula C29H36N4O5 M. Wt 520.62
Purity 98% Storage Store at 4-8°C
Description in vitro: Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells. Check for active clinical trials or closed clinical trials using this agent. in vivo: Z-360 is a novel orally active CCK-2/gastrin receptor antagonist, significantly inhibits the growth of subcutaneous xenografts of human pancreatic tumor cells in mice, and that Z-360 combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice.
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