ARN272

  • Chemical Properties
CAS No. 488793-85-7 Cat. No. BCP17386
Name ARN272
Synonyms ARN-272;ARN 272;
Formula C27H20N4O2 M. Wt 432.47
  • Biological Activity
Description ARN 272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50 = 1.8 μM); cytosolic variant of FAAH-1 that binds anandamide. Attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Exhibits analgesic effects in rodent models of CB1-mediated nociceptive and inflammatory pain.
Pathways Protease/Metabolic Enzyme Neuro Signaling Pathway 
Targets FAAH 

Structure

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